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Basic information of Ercc8 :

Official Symbol of Gene Ercc8
Species Mus musculus
Entrez Gene ID 71991
Official Full Name excision repaiross-complementing rodent repair deficiency, complementation group 8
Also known as Csa; Ckn1; 2410022P04Rik; 2810431L23Rik; 4631412O06Rik; B130065P18Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000021694 AllianceGenome:MGI:1919241
Map Location 13; 13 D2.1
Drug CsA treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 21092405
Year 2011
Title Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice?

Results of multiple sclerosis :

Result During a follow-up period of 20 days, the observed clinical benefit could be attributed solely to CsA treatment.
Mechanism/pathway In order to avoid acute or chronic rejection of cellular transplant in the CNS, as previously demonstrated by us and others.