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Basic information of Kcna3 :

Official Symbol of Gene Kcna3
Species Rattus norvegicus
Entrez Gene ID 29731
Official Full Name potassium voltage-gated channel subfamily A member 3
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000062002 AllianceGenome:RGD:2951
Map Location 2q34
Drug ADWX-1
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Sprague-Dawley (SD) rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 22761436
Year 2012
Title Selective inhibition of CCR7(-) effector memory T cell activation by a novel peptide targeting Kv1.3 channel in a rat experimental autoimmune encephalomyelitis model

Results of multiple sclerosis :

Result ADWX-1 selectively inhibits TEM activation through regulating both Kv1.3 activity and expression
Mechanism/pathway ADWX-1 ameliorates EAE with a cell selectivity mechanism