Basic information of Mog :

Official Symbol of Gene	Mog
Species	Rattus norvegicus
Entrez Gene ID	24558
Official Full Name	myelin oligodendrocyte glycoprotein
Also known as	N/A
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000000775 AllianceGenome:RGD:3102
Map Location	20p12
Drug	MOG-Ig gene therapy(retrovirally transduced B cells)
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	15093551
Year	2004
Title	A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP

Results of multiple sclerosis :

Result	Inhibition of antibody production specific for myelin oligodendrocyte glycoprotein (MOG) and suppression of chronic EAE induced by MOG in susceptible mice can be elicited by MOG-Ig gene therapy.
Mechanism/pathway	Tolerance induction is an important way of modulating the immune response in an antigen-specific manner to potentially hinder or prevent the progression of the disease.