Details

Home Details


Basic information of Ccl4 :

Official Symbol of Gene Ccl4
Species Mus musculus
Entrez Gene ID 20303
Official Full Name chemokine (C-C motif) ligand 4
Also known as Act-2; Mip1b; Scya4; MIP-1B; AT744.1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000018930 AllianceGenome:MGI:98261
Map Location 11 C; 11 51.09 cM
Drug treated with decitabine
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 28915632
Year 2017
Title Decitabine inhibits T cell proliferation via a novel TET2-dependent mechanism and exerts potent protective effect in mouse auto- and allo-immunity models

Results of multiple sclerosis :

Result Decitabine inhibits proinflammatory response of CNS in EAE mice.
Mechanism/pathway N/A