Details

Home Details


Basic information of Arg1 :

Official Symbol of Gene Arg1
Species Mus musculus
Entrez Gene ID 11846
Official Full Name arginase, liver
Also known as AI; PGIF; Arg-1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000019987 AllianceGenome:MGI:88070
Map Location 10; 10 A4
Drug ABH
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 (B6) mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 12941151
Year 2003
Title Arginase and autoimmune inflammation in the central nervous system

Results of multiple sclerosis :

Result ABH treatment not only delayed the onset but also reduced the severity of the disease.
Mechanism/pathway ABH is effective in inhibiting arginase activities in the central nervous system.