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Basic information of Gnpat :

Official Symbol of Gene Gnpat
Species Rattus norvegicus
Entrez Gene ID 84470
Official Full Name glyceronephosphate O-acyltransferase
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000019205 AllianceGenome:RGD:620179
Map Location 19q12
Drug lovastatin
Interaction Type activator

Sample information of multiple sclerosis:

Descent female Lewis rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 15353207
Year 2004
Title Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment

Results of multiple sclerosis :

Result Lovastatin treatment reduced the effect produced by EAE disease on the repression of expression of transcripts encoding peroxisomal proteins.Lovastatin treatment significantly up-regulated the expression of catalase, acyl CoA oxidase DHAP-AT and PEX6 in EAE Lewis rats compared with untreated counterparts.
Mechanism/pathway At the mRNA level, enhanced stability or increased transcriptional activity.