Basic information of Mbp :

Official Symbol of Gene	Mbp
Species	Mus musculus
Entrez Gene ID	17196
Official Full Name	myelin basic protein
Also known as	jve; mld; shi; Hmbpr; golli-mbp
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000041607 AllianceGenome:MGI:96925
Map Location	18 E3; 18 55.84 cM
Drug	I-AS protein plus MBP 91-103 complex
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	female SJL/J mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	1722335
Year	1991
Title	Antigen-specific therapy of experimental allergic encephalomyelitis by soluble class II major histocompatibility complex-peptide complexes

Results of multiple sclerosis :

Result	I-As protein were effective in preventing experimental allergic encephalomyelitis and prevented mortality and significantly reduced paralysis induced by immunization with the encephalitogenic proteolipoprotein peptide and prevented the development of inflammatory lesions characteristic of experimental allergic encephalomyelitis.
Mechanism/pathway	Experimental allergic encephalomyelitis is a T-cell-mediated, major histocompatibility complex (MHC) class II gene-linked autoimmune demyelinating disease of the central nervous system.