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Basic information of Cnr1 :

Official Symbol of Gene Cnr1
Species Rattus norvegicus (Norway rat)
Entrez Gene ID 25248
Official Full Name cannabinoid receptor 1
Also known as SKR6R
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000008223 AllianceGenome:RGD:2369
Map Location 5q21
Drug rolipram
Interaction Type activator

Sample information of multiple sclerosis:

Descent Lewis rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 16242629
Year 2005
Title Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis

Results of multiple sclerosis :

Result supresses EAE in different species,attenuated clinical decline, reduced motor inhibition, and normalized CB1 receptor gene expression in the basal ganglia.
Mechanism/pathway an inhibitor of type IV phosphodiesterase