Basic information of Cnr1 :

Official Symbol of Gene	Cnr1
Species	Rattus norvegicus (Norway rat)
Entrez Gene ID	25248
Official Full Name	cannabinoid receptor 1
Also known as	SKR6R
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000008223 AllianceGenome:RGD:2369
Map Location	5q21
Drug	AM404,arvanil,OMDM2
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	Lewis rats
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	16242629
Year	2005
Title	Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis

Results of multiple sclerosis :

Result	We found that the administration of the endocannabinoid transport inhibitors ,AM404 and arvanil,was effective at reducing the magnitude of the neurological decline in EAE rats . OMDM2 , another endocannabinoid transport inhibitor also reduced neurological decline in EAE rats.
Mechanism/pathway	Based on the occurrence of reduced endocannabinoid levels in the brain of EAE rats,enhancing endocannabinoid activity by inhibiting endocannabinoid transport is beneficial to reduce clinical injury in EAE rats.