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Basic information of Trpv1 :

Official Symbol of Gene Trpv1
Species Rattus norvegicus (Norway rat)
Entrez Gene ID 83810
Official Full Name transient receptor potential cation channel, subfamily V, member 1
Also known as Vr1; Vr1l1; VR.5'sv; TRPV1_SON
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000019486 AllianceGenome:RGD:628841
Map Location 10q24
Drug AM404,arvanil
Interaction Type activator

Sample information of multiple sclerosis:

Descent Lewis rats
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 16242629
Year 2005
Title Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis

Results of multiple sclerosis :

Result We found that the administration of the vanilloid TRPV1 receptor agonists,AM404 and arvanil , was effective at reducing the magnitude of the neurological decline in EAE rats .
Mechanism/pathway capability to activate TRPV1 receptors