Details

Home Details


Basic information of IFNG :

Official Symbol of Gene IFNG
Species Homo sapiens
Entrez Gene ID 3458
Official Full Name interferon gamma
Also known as IFG; IFI; IMD69
Gene Type protein coding
dbXrefs Ensembl:ENSG00000111537 MIM:147570; AllianceGenome:HGNC:5438
Map Location 12q15
Drug IFN-β
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent 372 ambulatory patients with relapsing-remitting multiple sclerosis (MS)
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 11902592
Year 2001
Title Interferon beta-lb is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. 1993 [classical article]

Results of multiple sclerosis :

Result the identification of a substantial reduction in the relapse rate and new demyelinating lesions on MR.
Mechanism/pathway The mechanism of action of IFN-β appears likely to be related to its in vitro effect in blocking the stimulation of MHC molecules by IFN-γ.