Basic information of F2r :

Official Symbol of Gene	F2r
Species	Mus musculus
Entrez Gene ID	14062
Official Full Name	coagulation factor II (thrombin) receptor
Also known as	Cf2r; Par1; ThrR
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000048376 AllianceGenome:MGI:101802
Map Location	13 D1; 13 50.21 cM
Drug	PAR-1 antagonist, FR171113 and SCH79797 dihydrochloride, a selective inhibitor of PAR-1
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	wild-type mice and NR4A2 cKO mice
Disease	late/chronic EAE

Literature information of multiple sclerosis :

Pubmed ID	26436530
Year	2015
Title	Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation

Results of multiple sclerosis :

Result	Cumulative disease burden were significantly suppressed in both wild-type mice and NR4A2 cKO mice.
Mechanism/pathway	CD4+ memory T cells and CD8+ T cells have been reported as mediating cytotolytic effects via granzyme B release.