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Basic information of Tnfsf4 :

Official Symbol of Gene Tnfsf4
Species Mus musculus
Entrez Gene ID 22164
Official Full Name tumor necrosis factor (ligand) superfamily, member 4
Also known as Ath1; gp34; Ath-1; Ox40l; TXGP1; CD134L; OX-40L; Tnlg2b; Txgp1l
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000026700 AllianceGenome:MGI:104511
Map Location 1 H2.1; 1 69.75 cM
Drug pOX40-TRAIL/ND(DNA encoding OX40-TRAIL cloned into the pND vector)
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent female C57BL/6 mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 21732666
Year 2011
Title A single intrathecal injection of DNA and an asymmetric cationic lipid as lipoplexes ameliorates experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result decreased severity of EAE and reduced inflammatory cell infiltrates beneath the meninges
Mechanism/pathway block pro-inflammatory signaling,inhibite pathogenic T cells