Basic information of Malt1 :

Official Symbol of Gene	Malt1
Species	Mus musculus
Entrez Gene ID	240354
Official Full Name	MALT1 paracaspase
Also known as	Pcasp1; A630046N12; D430033E09Rik
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000032688 AllianceGenome:MGI:2445027
Map Location	18; 18 E1
Drug	mepazine
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	Male mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	25043939
Year	2014
Title	Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis

Results of multiple sclerosis :

Result	Treatment with mepazine reduces experimental autoimmune encephalomyelitis (EAE) severity
Mechanism/pathway	Reduced central nervous system demyelination, axonal damage and inflammatory cell infiltration and cytokine expression in mepazine-treated mice