Basic information of Hspd1 :

Official Symbol of Gene	Hspd1
Species	Mus musculus
Entrez Gene ID	15510
Official Full Name	heat shock protein 1 (chaperonin)
Also known as	60kDa; CPN60; Hsp60; HSP-60; HSP-65
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000025980 AllianceGenome:MGI:96242
Map Location	1; 1 C1.2
Drug	pVAXhsp65
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	24439542
Year	2014
Title	Downmodulation of peripheral MOG-specific immunity by pVAXhsp65 treatment during EAE does not reach the CNS

Results of multiple sclerosis :

Result	These results indicate that hsp65, administered as a DNA vaccine, was not therapeutic for EAE
Mechanism/pathway	Although pVAXhsp65 was immunogenic for mice with EAE and downmodulated specific cytokine induction byMOG, therapy was not able to decrease clinical severity nor tomodify immunologic parameters in the CNS