Basic information of Il4 :

Official Symbol of Gene	Il4
Species	Mus musculus
Entrez Gene ID	16189
Official Full Name	interleukin 4
Also known as	Il-4; BSF-1
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000000869 AllianceGenome:MGI:96556
Map Location	11 B1.3; 11 31.97 cM
Drug	HSV-1-derived vector containing the gene of the anti-inflammatory cytokine IL-4
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	BALB/c
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	10854655
Year	2000
Title	Cytokine therapy in immune-mediated demyelinating diseases of the central nervous system: a novel gene therapy approach

Results of multiple sclerosis :

Result	Compared to controls, mice affected by experimental autoimmune encephalomyelitis (EAE) and i.c. injected with an HSV-1-derived vector containing the gene of the anti-inflammatory cytokine IL-4 showed a significant amelioration of clinical and pathological EAE signs
Mechanism/pathway	non-toxic system to deliver cytokines within the central nervous system (CNS)