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Basic information of IFNB1 :

Official Symbol of Gene IFNB1
Species Homo sapiens
Entrez Gene ID 3456
Official Full Name interferon beta 1
Also known as IFB; IFF; IFNB; IFN-beta
Gene Type N/A
dbXrefs Ensembl:ENSG00000171855 MIM:147640; AllianceGenome:HGNC:5434
Map Location 9p21.3
Drug IFN-β
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent American
Disease RRMS

Literature information of multiple sclerosis :

Pubmed ID 21658727
Year 2011
Title Quantitative differences in the immunomodulatory effects of Rebif and Avonex in IFN-å°¾ 1a treated multiple sclerosis patients

Results of multiple sclerosis :

Result the higher dosed, more frequently administered IFN-å°¾ 1a Rebif when compared to IFN-å°¾ 1a Avonex has more potent immunomodulatory effects
Mechanism/pathway The STAT1-inducible genes IP-10 and caspase 1 were significantly increased with Rebif compared to Avonex.