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Basic information of Birc5 :

Official Symbol of Gene Birc5
Species Mus musculus
Entrez Gene ID 11799
Official Full Name baculoviral IAP repeat-containing 5
Also known as Api4; TIAP; AAC-11; survivin40
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000017716 AllianceGenome:MGI:1203517
Map Location 11; 11 E2
Drug treated with YM155
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 mice
Disease N/A

Literature information of multiple sclerosis :

Pubmed ID 31489534
Year 2019
Title Sepantronium Bromide (YM155), A Small Molecule Survivin Inhibitor, Promotes Apoptosis by Induction of Oxidative Stress, Worsens the Behavioral Defcits and Develops an Early Model of Toxic Demyelination: In Vivo and InSilico Study

Results of multiple sclerosis :

Result In the cuYM group, the expression of BIRC5, BIRC4 and NAIP was reduced.
Mechanism/pathway N/A