Basic information of IFNB1 :
| Official Symbol of Gene | IFNB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3456 |
| Official Full Name | interferon beta 1 |
| Also known as | IFB; IFF; IFNB; IFN-beta |
| Gene Type | N/A |
| dbXrefs | Ensembl:ENSG00000171855 MIM:147640; AllianceGenome:HGNC:5434 |
| Map Location | 9p21.3 |
| Drug | IFN-β |
| Interaction Type | inhibitor |
Sample information of multiple sclerosis:
| Descent | Danes |
| Disease | MS |
Literature information of multiple sclerosis :
| Pubmed ID | 25738751 |
| Year | 2015 |
| Title | Endogenous Interferon-å°¾-Inducible Gene Expression and Interferon-å°¾-Treatment Are Associated with Reduced T Cell Responses to Myelin Basic Protein in Multiple Sclerosis |
Results of multiple sclerosis :
| Result | spontaneous expression of interferon-å°¾-inducible genes in peripheral blood mononuclear cells from untreated multiple sclerosis patients and treatment with interferon-å°¾ are associated with reduced myelin basic protein-induced T-cell responses. Reduced myelin basic protein-induced CD4+ T-cell autoreactivity in interferon-å°¾-treated multiple sclerosis patients may be mediated by monocyte-derived interleukin-10. |
| Mechanism/pathway | found an association of high expression levels of interferon-å°¾-inducible genes with an increased expression of interleukin-10 and a milder disease course in untreated multiple sclerosis patients |
