Details

Home Details


Basic information of Nqo1 :

Official Symbol of Gene Nqo1
Species Mus musculus
Entrez Gene ID 18104
Official Full Name NAD(P)H dehydrogenase, quinone 1
Also known as Dtd; Ox1; Qr1; Dia4; Nmo1; Ox-1; Nmo-1; Nmor1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000003849 AllianceGenome:MGI:103187
Map Location 8 D3; 8 54.08 cM
Drug TFM-735
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 J
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 28246026
Year 2017
Title The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice

Results of multiple sclerosis :

Result the expression of the Nrf2 target gene Nqo1 increased in the brain and spleen, disease severity was ameliorated
Mechanism/pathway N/A