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Basic information of Mbp :

Official Symbol of Gene Mbp
Species Mus musculus
Entrez Gene ID 17196
Official Full Name myelin basic protein
Also known as jve; mld; shi; Hmbpr; golli-mbp
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000041607 AllianceGenome:MGI:96925
Map Location 18 E3; 18 55.84 cM
Drug MBP-PE 40
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 10424450
Year 1999
Title A novel antigen-toxin chimeric protein: myelin basic protein-pseudomonas exotoxin (MBP-PE 40) for treatment of experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result A chimeric protein such as MBP-PE40 presents a novel prototype of chimeric proteins, composed of antigen/peptide-toxin, that could prove to be an efficient and specific immunotherapeutic agent for autoimmune diseases in which a known antigen is involved
Mechanism/pathway cytotoxic to various anti-MBP T cells