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Basic information of EOMES :

Official Symbol of Gene EOMES
Species Homo sapiens
Entrez Gene ID 8320
Official Full Name eomesodermin
Also known as TBR2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000163508 MIM:604615; AllianceGenome:HGNC:3372
Map Location 3p24.1
Drug glatiramer acetate (GA)
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Russians
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 29095108
Year 2017
Title Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis: the impact of genome-wide association studies identified disease risk loci

Results of multiple sclerosis :

Result The biallelic combinations including EOMES, CLEC16A, IL22RA2, PVT1, TYK2, CD6, IL7RA and IRF8 genes were associated with response to GA with increased significance level
Mechanism/pathway epistasic interactions or additive effects