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Basic information of CLEC16A :

Official Symbol of Gene CLEC16A
Species Homo sapiens
Entrez Gene ID 23274
Official Full Name C-type lectin domain containing 16A
Also known as Gop-1; KIAA0350
Gene Type protein coding
dbXrefs Ensembl:ENSG00000038532 MIM:611303; AllianceGenome:HGNC:29013
Map Location 16p13.13
Drug glatiramer acetate (GA)
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Russians
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 29095108
Year 2017
Title Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis: the impact of genome-wide association studies identified disease risk loci

Results of multiple sclerosis :

Result The biallelic combinations including EOMES, CLEC16A, IL22RA2, PVT1, TYK2, CD6, IL7RA and IRF8 genes were associated with response to GA with increased significance level
Mechanism/pathway epistasic interactions or additive effects