Basic information of TYK2 :

Official Symbol of Gene	TYK2
Species	Homo sapiens
Entrez Gene ID	7297
Official Full Name	tyrosine kinase 2
Also known as	JTK1; IMD35
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000105397 MIM:176941; AllianceGenome:HGNC:12440
Map Location	19p13.2
Drug	glatiramer acetate (GA)
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	Russians
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	29095108
Year	2017
Title	Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis: the impact of genome-wide association studies identified disease risk loci

Results of multiple sclerosis :

Result	The biallelic combinations including EOMES, CLEC16A, IL22RA2, PVT1, TYK2, CD6, IL7RA and IRF8 genes were associated with response to GA with increased significance level
Mechanism/pathway	epistasic interactions or additive effects