Details

Home Details


Basic information of CD6 :

Official Symbol of Gene CD6
Species Homo sapiens
Entrez Gene ID 923
Official Full Name CD6 molecule
Also known as TP120
Gene Type protein coding
dbXrefs Ensembl:ENSG00000013725 MIM:186720; AllianceGenome:HGNC:1691
Map Location 11q12.2
Drug glatiramer acetate (GA)
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Russians
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 29095108
Year 2017
Title Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis: the impact of genome-wide association studies identified disease risk loci

Results of multiple sclerosis :

Result The biallelic combinations including EOMES, CLEC16A, IL22RA2, PVT1, TYK2, CD6, IL7RA and IRF8 genes were associated with response to GA with increased significance level
Mechanism/pathway epistasic interactions or additive effects