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Basic information of TNF :

Official Symbol of Gene TNF
Species Homo sapiens
Entrez Gene ID 7124
Official Full Name tumor necrosis facto
Also known as DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Gene Type protein coding
dbXrefs Ensembl:ENSG00000232810 MIM:191160; AllianceGenome:HGNC:11892
Map Location 6p21.33
Drug Lipopolysaccharide
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL6
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 17055066
Year 2007
Title Lipopolysaccharide pretreatment modulates the disease course in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result Consistently led to a delayed onset of disease but not to a reduction in disease severity
Mechanism/pathway affects antigen presentation and may modulate the expression of inflammatory regulators that impact the autoimmune disease course