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Basic information of Il17a :

Official Symbol of Gene Il17a
Species Mus musculus
Entrez Gene ID 16171
Official Full Name interleukin 17A
Also known as Il17; Ctla8; IL-17; Ctla-8; IL-17A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000025929 AllianceGenome:MGI:107364
Map Location 1; 1 A4
Drug ATRA and calcitriol
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL6
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 27996890
Year 2016
Title The effect of 1, 25(OH)2 D3 (calcitriol) alone and in combination with all-trans retinoic acid on ROR-纬t, IL-17, TGF-尾, and FOXP3 gene expression in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result The expression of FOXP3 and TGF-å°¾ genes in the splenocytes of combination-treated and calcitriol alone-treated mice was significantly increased compared to vehicle group (P< 0.05).
Mechanism/pathway N/A