Basic information of Tgfbr1 :
| Official Symbol of Gene | Tgfbr1 |
| Species | Mus musculus |
| Entrez Gene ID | 21812 |
| Official Full Name | transforming growth factor, beta receptor I |
| Also known as | ALK5; ESK2; Alk-5; TGFR-1; TbetaRI; TbetaR-I |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000007613 AllianceGenome:MGI:98728 |
| Map Location | 4 B1; 4 26.02 cM |
| Drug | ATRA and calcitriol |
| Interaction Type | inhibitor |
Sample information of multiple sclerosis:
| Descent | C57BL6 |
| Disease | EAE |
Literature information of multiple sclerosis :
| Pubmed ID | 27996890 |
| Year | 2016 |
| Title | The effect of 1, 25(OH)2 D3 (calcitriol) alone and in combination with all-trans retinoic acid on ROR-纬t, IL-17, TGF-尾, and FOXP3 gene expression in experimental autoimmune encephalomyelitis |
Results of multiple sclerosis :
| Result | The expression of FOXP3 and TGF-å°¾ genes in the splenocytes of combination-treated and calcitriol alone-treated mice was significantly increased compared to vehicle group (P< 0.05). |
| Mechanism/pathway | N/A |
