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Basic information of Cxcl12 :

Official Symbol of Gene Cxcl12
Species Mus musculus
Entrez Gene ID 20315
Official Full Name chemokine (C-X-C motif) ligand 12
Also known as Pbsf; Sdf1; Tlsf; Tpar1; Scyb12
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000061353 AllianceGenome:MGI:103556
Map Location 6 54.81 cM; 6 F1
Drug 4-Methylumbelliferone (4MU)
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL6
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 24973214
Year 2014
Title Inhibition of Hyaluronan Synthesis Protects against Central Nervous System (CNS) Autoimmunity and Increases CXCL12 Expression in the Inflamed CNS

Results of multiple sclerosis :

Result Inhibition of hyaluronan synthesis protects against CNS inflammation.
Mechanism/pathway modulates T-cell responses, and prevents CXCL12 suppression within inflamed and non-inflamed CNS tissue