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Basic information of IL10 :

Official Symbol of Gene IL10
Species Homo sapiens
Entrez Gene ID 3586
Official Full Name interleukin 10
Also known as CSIF; TGIF; GVHDS; IL-10; IL10A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136634 MIM:124092; AllianceGenome:HGNC:5962
Map Location 1q32.1
Drug IL10
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent SJL/J and CSJLF1/J
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 10075984
Year 1999
Title Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis

Results of multiple sclerosis :

Result This study demonstrates that IL-10 can prevent EAE completely if present at appropriate levels and times during disease induction.
Mechanism/pathway Myelin-reactive T helper 1 cells are induced but nonpathogenic in the IL-10 transgenic mice