Details

Home Details


Basic information of Mbp :

Official Symbol of Gene Mbp
Species Rattus norvegicus
Entrez Gene ID 24547
Official Full Name myelin basic protein
Also known as Mbps
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000016516 AllianceGenome:RGD:3054
Map Location 18q12.3
Drug combined therapy of vitamins A and C
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Lewis rats
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 35072933
Year 2022
Title Therapeutic Potential of Combined Therapy of Vitamin A and Vitamin C in the Experimental Autoimmune Encephalomyelitis (EAE) in Lewis Rats

Results of multiple sclerosis :

Result Our findings suggest that combined therapy of vitamins A and C protect myelin damage via increasing BDNF and MBP levels in the CNS and causes anti-inflammatory, antioxidant and neuroprotective impacts in the EAE model.
Mechanism/pathway N/A