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Basic information of Mt2 :

Official Symbol of Gene Mt2
Species Mus musculus
Entrez Gene ID 17750
Official Full Name metallothionein 2
Also known as Mt-2; MT-II
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000031762 AllianceGenome:MGI:97172
Map Location 8 C5; 8 46.32 cM
Drug MT2
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6 and TgMT mice
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 30543238
Year 2019
Title Mouse metallothionein-1 and metallothionein-2 are not biologically interchangeable in an animal model of multiple sclerosis, EAE

Results of multiple sclerosis :

Result the administration of MT1 and MT2 showed a clear trend to decrease the clinical signs, but only the MT2 isoform did it significantly.
Mechanism/pathway N/A