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Basic information of Akt2 :

Official Symbol of Gene Akt2
Species Rattus norvegicus
Entrez Gene ID 25233
Official Full Name AKT serine/threonine kinase 2
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000018677 AllianceGenome:RGD:2082
Map Location 1q21
Drug FTY720
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent CD38-deficient
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 27519689
Year 2016
Title Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis

Results of multiple sclerosis :

Result we have shown attenuation ofEAE after treatment with FTY720 or reduced EAE severity in CD38-deficient mice
Mechanism/pathway treatment of MOG-induced EAE with FTY720 impacts the gene expression of the genes that are involved in encephalitogenic immune responses.