Basic information of Nkx2-2 :

Official Symbol of Gene	Nkx2-2
Species	Rattus norvegicus
Entrez Gene ID	1308443
Official Full Name	NK2 homeobox 2
Also known as	N/A
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000012728 AllianceGenome:RGD:1308443
Map Location	3q41
Drug	Teriflunomide
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	Wistar rat
Disease	N/A

Literature information of multiple sclerosis :

Pubmed ID	29534752
Year	2018
Title	Teriflunomide promotes oligodendroglial differentiation and myelination

Results of multiple sclerosis :

Result	Quantitative RT-PCR after 1d revealed that stimulation of primary rat OPCs with tolerated concentration profiles of teriflunomide led to a significant upregulation of CNPase, TAp73, Mash1/Ascl1, Myrf, Nkx2.2, PLP, and Sox 10 transcript levels
Mechanism/pathway	Short-term teriflunomide pulses can efficiently promote oligodendroglial cell differentiation suggesting that young, immature cells could benefit from such stimulation.