Basic information of FXN :

Official Symbol of Gene	FXN
Species	Homo sapiens
Entrez Gene ID	3951
Official Full Name	frataxin
Also known as	FA; X25; CyaY; FARR; FRDA
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000165060 MIM:606829; AllianceGenome:HGNC:3951
Map Location	9q21.11
Drug	Dimethyl fumarate
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	31158268
Year	2019
Title	Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia

Results of multiple sclerosis :

Result	DMF dosed Multiple Sclerosis (MS) patients showed significant increase in FXN expression by ~85%
Mechanism/pathway	As a potential consequence, we observe significant reduction in both R-loop formation and transcriptional pausing thereby significantly increasing FXN expression