Basic information of Tbx21 :

Official Symbol of Gene	Tbx21
Species	Mus musculus
Entrez Gene ID	1888984
Official Full Name	T-box 21
Also known as	TBT1; Tbet; Tblym
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000001444 AllianceGenome:MGI:1888984
Map Location	11; 11 D
Drug	Gemfibrozil
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	19299749
Year	2009
Title	Transcriptional Modulation of the Immune Response by Peroxisome Proliferator-Activated Receptor-α Agonists in Autoimmune Disease

Results of multiple sclerosis :

Result	We demonstrated that treatment with gemfibrozil increases expression of the Th2 transcription factor GATA-3 and decreases expression of the Th1 transcription factor T-bet in vitro and directly ex vivo
Mechanism/pathway	Therefore, if PPARα, through interaction with its ligand, can regulate either of these transcription factors directly or indirectly, this could result in the regulation of the other transcription factor.