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Basic information of Il4 :

Official Symbol of Gene Il4
Species Mus musculus
Entrez Gene ID 96556
Official Full Name interleukin 4
Also known as Il-4; BSF-1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000000869 AllianceGenome:MGI:96556
Map Location 11 B1.3; 11 31.97 cM
Drug Gemfibrozil
Interaction Type activator

Sample information of multiple sclerosis:

Descent C57BL/6
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 19299749
Year 2009
Title Transcriptional Modulation of the Immune Response by Peroxisome Proliferator-Activated Receptor-α Agonists in Autoimmune Disease

Results of multiple sclerosis :

Result These data, in combination with the inability of gemfibrozil to increase IL-4 production when PPARα is silenced (Fig. 4), suggest that PPARα can transactivate the IL-4 promoter and that the binding is functional.
Mechanism/pathway that PPARα can directly transactivate the IL-4 gene