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Basic information of RORC :

Official Symbol of Gene RORC
Species Homo sapiens
Entrez Gene ID 10260
Official Full Name RAR related orphan receptor C
Also known as TOR; RORG; RZRG; IMD42; NR1F3; RZR-GAMMA
Gene Type protein coding
dbXrefs Ensembl:ENSG00000143365 MIM:602943; AllianceGenome:HGNC:10260
Map Location 1q21.3
Drug G2013
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 32103523
Year 2020
Title Pivotal cytokines and their transcription factors are the targets of guluronic acid (G2013) for inhibiting the immunopathogenesis process of multiple sclerosis

Results of multiple sclerosis :

Result the results show that G2013 is able to significantly reduce the gene expression of IL-22, AHR, RORC, and T-bet
Mechanism/pathway he α-L-guluronic acid (G2013), is a novel immunosuppressive drug