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Basic information of TBX21 :

Official Symbol of Gene TBX21
Species Homo sapiens
Entrez Gene ID 11599
Official Full Name T-box transcription factor 21
Also known as TBET; IMD88; T-PET; T-bet; TBLYM
Gene Type protein coding
dbXrefs Ensembl:ENSG00000073861 MIM:604895; AllianceGenome:HGNC:11599
Map Location 17q21.32
Drug G2013
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 32103523
Year 2020
Title Pivotal cytokines and their transcription factors are the targets of guluronic acid (G2013) for inhibiting the immunopathogenesis process of multiple sclerosis

Results of multiple sclerosis :

Result the results show that G2013 is able to significantly reduce the gene expression of IL-22, AHR, RORC, and T-bet
Mechanism/pathway he α-L-guluronic acid (G2013), is a novel immunosuppressive drug