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Basic information of LILRB2 :

Official Symbol of Gene LILRB2
Species Homo sapiens
Entrez Gene ID 10288
Official Full Name leukocyte immunoglobulin like receptor B2
Also known as ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10
Gene Type protein coding
dbXrefs Ensembl:ENSG00000131042 MIM:604815; AllianceGenome:HGNC:6606
Map Location 19q13.42
Drug IFN-β treatment
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent 227 mononuclear cell samples
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 31648992
Year 2017
Title Interferon-β corrects massive gene dysregulation in multiple sclerosis: Short-term and long-term effects on immune regulation and neuroprotection

Results of multiple sclerosis :

Result Surprisingly, short-term IFN-β induced little shift in Th1/Th17/Th2 gene expression, but up-regulated immune-inhibitory genes(ILT, IDO1, PD-L1).
Mechanism/pathway N/A