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Basic information of CCL2 :

Official Symbol of Gene CCL2
Species Homo sapiens
Entrez Gene ID 10618
Official Full Name C-C motif chemokine ligand 2
Also known as HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Gene Type protein coding
dbXrefs nsembl:ENSG00000108691 MIM:158105; AllianceGenome:HGNC:10618
Map Location 17q12
Drug interferon beta
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 19667211
Year 2009
Title Enhancement of chemokine expression by interferon beta therapy in patients with multiple sclerosis

Results of multiple sclerosis :

Result CCL1, CCL2, CCL7, CXCL10, CXCL11, and CCR1 gene expression was strongly upregulated in interferon beta-treated
Mechanism/pathway The peripheral upregulation of these chemokines may reduce the chemoattraction of immune cells to the central nervous system and thus add to the therapeutic effects of interferon beta