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Basic information of Il6 :

Official Symbol of Gene Il6
Species Rattus norvegicus
Entrez Gene ID 2901
Official Full Name interleukin 6
Also known as ILg6; Ifnb2
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000010278 AllianceGenome:RGD:2901
Map Location 4q11
Drug GW 501516
Interaction Type activator

Sample information of multiple sclerosis:

Descent N/A
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 19422681
Year 2009
Title Effects of the PPAR-beta agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination

Results of multiple sclerosis :

Result it increased IL-6 m-RNA expression
Mechanism/pathway the protective effects of PPAR-beta agonists observed in vivo can be attributed to their anti-inflammatory properties rather than to a direct protective or trophic effect on oligodendrocytes