Basic information of IL27 :

Official Symbol of Gene	IL27
Species	Homo sapiens
Entrez Gene ID	19157
Official Full Name	interleukin 27
Also known as	p28; IL30; IL-27; IL27A; IL-27A; IL27p28
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000197272 MIM:608273; AllianceGenome:HGNC:19157
Map Location	16p12.1-p11.2
Drug	Simvastatin
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	RRMS
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	23076801
Year	2013
Title	Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen presentation by DCs in patients with relapsing remitting multiple sclerosis

Results of multiple sclerosis :

Result	We report that simvastatin inhibits IL-1β, IL-23, TGF-β, IL-21, IL-12p70, and induces IL-27 secretion from DCs in RRMS patients, providing an inhibitory cytokine milieu for Th17 and Th1-cell differentiation
Mechanism/pathway	widely used cholesterol-lowering agents, have also been demonstrated to have antiinflammatory effects