Basic information of Il10 :

Official Symbol of Gene	Il10
Species	Mus musculus
Entrez Gene ID	96537
Official Full Name	interleukin 10
Also known as	CSIF; If2a; Il-10
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537
Map Location	1 E4; 1 56.89 cM
Drug	GSK3
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	B10.PL (H2u) mice
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	25627813
Year	2015
Title	Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter

Results of multiple sclerosis :

Result	treatment of Th1 and Th2 cells with GSK3 inhibitors dramatically increased production of IL-10
Mechanism/pathway	The serine/threonine kinase glycogen synthase kinase-3 (GSK3) plays an important role in balancing pro- and anti-inflammatory cytokine