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Basic information of IL10 :

Official Symbol of Gene IL10
Species Homo sapiens
Entrez Gene ID 5962
Official Full Name interleukin 10
Also known as CSIF; TGIF; GVHDS; IL-10; IL10A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136634 MIM:124092; AllianceGenome:HGNC:5962
Map Location 1q32.1
Drug GSK3
Interaction Type activator

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 25627813
Year 2015
Title Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter

Results of multiple sclerosis :

Result GSK3 inhibition also led to upregulation of IL-10 among Th1, Th2, and Th17 subsets isolated from human blood
Mechanism/pathway The serine/threonine kinase glycogen synthase kinase-3 (GSK3) plays an important role in balancing pro- and anti-inflammatory cytokine