Basic information of NQO1 :

Official Symbol of Gene	NQO1
Species	Homo sapiens
Entrez Gene ID	2874
Official Full Name	NAD(P)H quinone dehydrogenase 1
Also known as	DTD; QR1; DHQU; DIA4; NMOR1; NMORI
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000181019 MIM:125860; AllianceGenome:HGNC:2874
Map Location	16q22.1
Drug	DMF
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	28156185
Year	2017
Title	Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies

Results of multiple sclerosis :

Result	In DMF-treated patients, a statistically significant induction of NQO1 was observed relative to baseline and compared to placebo
Mechanism/pathway	DMF activated the nuclear factor E2-related factor 2 (Nrf2) pathway