Basic information of IL6 :

Official Symbol of Gene	IL6
Species	Homo sapiens
Entrez Gene ID	6018
Official Full Name	interleukin 6
Also known as	CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018
Map Location	7p15.3
Drug	Simvastatin
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	RRMS
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	18453621
Year	2008
Title	Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes

Results of multiple sclerosis :

Result	Our results demonstrated statin-mediated increases in suppressor of cytokine secretion (SOCS) 3 and suppressor of cytokine secretion 7, which negatively regulate the STAT/JAK signal transduction pathway and IL-6 and IL-23 gene expression in monocytes
Mechanism/pathway	These results provide evidence for the novel immunomodulatory mechanisms of statins, which selectively target the regulation of cytokine transcription involved in the development of the human autoimmune response