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Basic information of TBX21 :

Official Symbol of Gene TBX21
Species Homo sapiens
Entrez Gene ID 11599
Official Full Name T-box transcription factor 21
Also known as TBET; IMD88; T-PET; T-bet; TBLYM
Gene Type protein coding
dbXrefs Ensembl:ENSG00000073861 MIM:604895; AllianceGenome:HGNC:11599
Map Location 17q21.32
Drug vitamin A
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 27122150
Year 2016
Title Retinyl Palmitate Supplementation Modulates T-bet and Interferon Gamma Gene Expression in Multiple Sclerosis Patients

Results of multiple sclerosis :

Result The results showed that after 6 months of supplementation, expression of IFN-γ and T-bet was significantly decreased
Mechanism/pathway These results provide evidence for the novel immunomodulatory mechanisms of statins, which selectively target the regulation of cytokine transcription involved in the development of the human autoimmune response