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Basic information of MIRLET7C :

Official Symbol of Gene MIRLET7C
Species Homo sapiens
Entrez Gene ID 31480
Official Full Name microRNA let-7c
Also known as LET7C; let-7c; MIRNLET7C; hsa-let-7c
Gene Type protein coding
dbXrefs Ensembl:ENSG00000199030 MIM:612144; miRBase:MI0000064; AllianceGenome:HGNC:31480
Map Location 21q21.1
Drug Natalizumab
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 24852919
Year 2014
Title Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients

Results of multiple sclerosis :

Result We found that the expression level of three miRNAs (let-7c, miR-125a-5p and miR-642) was affected after 6 months of therapy
Mechanism/pathway Natalizumab has shown its efficacy in reducing multiple sclerosis (MS) relapses and progression of disability