Basic information of CD274 :
| Official Symbol of Gene | CD274 |
| Species | Homo sapiens |
| Entrez Gene ID | 29126 |
| Official Full Name | CD274 molecule |
| Also known as | B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000120217 MIM:605402; AllianceGenome:HGNC:17635 |
| Map Location | 9p24.1 |
| Drug | IFN-β treatment |
| Interaction Type | inhibitor |
Sample information of multiple sclerosis:
| Descent | 227 mononuclear cell samples |
| Disease | MS |
Literature information of multiple sclerosis :
| Pubmed ID | 31648992 |
| Year | 2017 |
| Title | Interferon-β corrects massive gene dysregulation in multiple sclerosis: Short-term and long-term effects on immune regulation and neuroprotection |
Results of multiple sclerosis :
| Result | Surprisingly, short-term IFN-β induced little shift in Th1/Th17/Th2 gene expression, but up-regulated immune-inhibitory genes(ILT, IDO1, PD-L1). |
| Mechanism/pathway | N/A |
